K12R (p.Lys12Arg) variant of DCC (Netrin receptor DCC)
K12R (p.Lys12Arg) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
K12R (p.Lys12Arg) variant details
- p.Lys12Arg
- gnomAD 18-52340822-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.08
- MetaLR 0.05
- MetaSVM -1.09
- CADD 17.50
- PolyPhen-2 0.00
- SIFT 0.94
- Population evidence available
- Structural context available
- Literature evidence available