I34T (p.Ile34Thr) variant of DCC (Netrin receptor DCC)
I34T (p.Ile34Thr) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
I34T (p.Ile34Thr) variant details
- p.Ile34Thr
- ExAC rs750760650
- gnomAD rs750760650
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.10
- CADD 22.40
- PolyPhen-2 0.04
- SIFT 0.14
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available