I34F (p.Ile34Phe) variant of DCC (Netrin receptor DCC)
I34F (p.Ile34Phe) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
I34F (p.Ile34Phe) variant details
- p.Ile34Phe
- cosmic curated COSV10050
- gnomAD rs1387130494
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.17
- CADD 22.40
- SIFT 0.23
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available