H26Q (p.His26Gln) variant of DCC (Netrin receptor DCC)
H26Q (p.His26Gln) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
H26Q (p.His26Gln) variant details
- p.His26Gln
- gnomAD 18-52340865-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.218
- REVEL 0.10
- MetaLR 0.10
- MetaSVM -1.07
- CADD 21.80
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available