H26L (p.His26Leu) variant of DCC (Netrin receptor DCC)
H26L (p.His26Leu) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
H26L (p.His26Leu) variant details
- p.His26Leu
- 1000Genomes rs568806828
- ExAC rs568806828
- TOPMed rs568806828
- gnomAD rs568806828
- Missense
- Variant Prioritization Score for Impact Estimate 0.255
- REVEL 0.21
- MetaLR 0.08
- MetaSVM -1.09
- CADD 19.40
- SIFT 0.65
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available