G19A (p.Gly19Ala) variant of DCC (Netrin receptor DCC)
G19A (p.Gly19Ala) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
G19A (p.Gly19Ala) variant details
- p.Gly19Ala
- gnomAD rs1983597057
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- REVEL 0.11
- MetaLR 0.08
- MetaSVM -1.06
- CADD 21.30
- PolyPhen-2 0.01
- SIFT 0.50
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available