F23I (p.Phe23Ile) variant of DCC (Netrin receptor DCC)
F23I (p.Phe23Ile) in DCC (Netrin receptor DCC) is a missense change. Clinical records from EBI and UniProt describe it as benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
F23I (p.Phe23Ile) variant details
- p.Phe23Ile
- 1000Genomes rs9951523
- ESP rs9951523
- ExAC rs9951523
- TOPMed rs9951523
- Benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.251
- REVEL 0.11
- MetaLR 0.07
- MetaSVM -1.10
- CADD 22.00
- SIFT 0.45
- EBI: Benign (in dbSNP:rs9951523)
- UniProt: Benign (in dbSNP:rs9951523)
- Population evidence available
- Structural context available