F15L (p.Phe15Leu) variant of DCC (Netrin receptor DCC)
F15L (p.Phe15Leu) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
F15L (p.Phe15Leu) variant details
- p.Phe15Leu
- 1000Genomes rs2144215891
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.20
- MetaLR 0.10
- MetaSVM -1.01
- CADD 24.10
- PolyPhen-2 0.83
- SIFT 0.33
- Most common in the 1KG:YRI population (allele frequency 0.0043)
- Structural context available