D60Y (p.Asp60Tyr) variant of DCC (Netrin receptor DCC)
D60Y (p.Asp60Tyr) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
D60Y (p.Asp60Tyr) variant details
- p.Asp60Tyr
- cosmic curated COSV59102
- TOPMed rs1347472471
- gnomAD rs1347472471
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.21
- CADD 22.90
- PolyPhen-2 0.74
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available