C7Y (p.Cys7Tyr) variant of DCC (Netrin receptor DCC)
C7Y (p.Cys7Tyr) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
C7Y (p.Cys7Tyr) variant details
- p.Cys7Tyr
- gnomAD rs866002143
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.12
- MetaLR 0.07
- MetaSVM -1.08
- CADD 21.30
- PolyPhen-2 0.00
- SIFT 0.91
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available