C7F (p.Cys7Phe) variant of DCC (Netrin receptor DCC)
C7F (p.Cys7Phe) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
C7F (p.Cys7Phe) variant details
- p.Cys7Phe
- gnomAD rs866002143
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.13
- MetaLR 0.06
- MetaSVM -1.08
- CADD 21.70
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available