A63V (p.Ala63Val) variant of DCC (Netrin receptor DCC)
A63V (p.Ala63Val) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
A63V (p.Ala63Val) variant details
- p.Ala63Val
- ExAC rs760978364
- TOPMed rs760978364
- gnomAD rs760978364
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.19
- CADD 18.10
- PolyPhen-2 0.42
- SIFT 0.09
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available