A20T (p.Ala20Thr) variant of DCC (Netrin receptor DCC)
A20T (p.Ala20Thr) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
A20T (p.Ala20Thr) variant details
- p.Ala20Thr
- gnomAD 18-52340845-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.06
- MetaLR 0.05
- MetaSVM -1.03
- CADD 22.30
- PolyPhen-2 0.01
- SIFT 0.71
- Population evidence available
- Structural context available
- Literature evidence available