A14S (p.Ala14Ser) variant of DCC (Netrin receptor DCC)
A14S (p.Ala14Ser) in DCC (Netrin receptor DCC) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
A14S (p.Ala14Ser) variant details
- p.Ala14Ser
- TOPMed rs1461748482
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.10
- MetaLR 0.07
- MetaSVM -1.06
- CADD 22.70
- PolyPhen-2 0.17
- SIFT 0.44
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available