Q66P (p.Gln66Pro) variant of DAP3 (P51398)
Q66P (p.Gln66Pro) in DAP3 (P51398) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
Q66P (p.Gln66Pro) variant details
- p.Gln66Pro
- gnomAD 1-155721545-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.25
- ESM-1b 1.00
- AlphaMissense 0.65
- CADD 23.10
- PolyPhen-2 0.56
- SIFT 0.01
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available