L36R (p.Leu36Arg) variant of DAP3 (P51398)
L36R (p.Leu36Arg) in DAP3 (P51398) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
L36R (p.Leu36Arg) variant details
- p.Leu36Arg
- gnomAD rs1295753368
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.08
- ESM-1b 0.00
- AlphaMissense 0.07
- CADD 14.40
- PolyPhen-2 0.12
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available