H63Y (p.His63Tyr) variant of DAP3 (P51398)
H63Y (p.His63Tyr) in DAP3 (P51398) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
H63Y (p.His63Tyr) variant details
- p.His63Tyr
- TOPMed rs1411226963
- gnomAD rs1411226963
- Missense
- Variant Prioritization Score for Impact Estimate 0.521
- REVEL 0.28
- ESM-1b 1.00
- AlphaMissense 0.16
- CADD 25.70
- PolyPhen-2 0.66
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available