F21S (p.Phe21Ser) variant of DAP3 (P51398)
F21S (p.Phe21Ser) in DAP3 (P51398) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
F21S (p.Phe21Ser) variant details
- p.Phe21Ser
- gnomAD 1-155717022-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.05
- ESM-1b 0.00
- AlphaMissense 0.11
- CADD 12.90
- PolyPhen-2 0.00
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available