D61Y (p.Asp61Tyr) variant of DAP3 (P51398)
D61Y (p.Asp61Tyr) in DAP3 (P51398) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
D61Y (p.Asp61Tyr) variant details
- p.Asp61Tyr
- cosmic curated COSV58021
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- REVEL 0.16
- ESM-1b 0.69
- AlphaMissense 0.07
- CADD 24.40
- PolyPhen-2 0.15
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available