Y151D (p.Tyr151Asp) variant of CYP51A1 (Lanosterol 14-alpha demethylase)
Y151D (p.Tyr151Asp) in CYP51A1 (Lanosterol 14-alpha demethylase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
Y151D (p.Tyr151Asp) variant details
- p.Tyr151Asp
- TOPMed rs312262912
- gnomAD rs312262912
- Missense
- Variant Prioritization Score for Impact Estimate 0.754
- REVEL 0.85
- MetaLR 0.59
- MetaSVM 0.44
- CADD 29.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available