P154T (p.Pro154Thr) variant of CYP51A1 (Lanosterol 14-alpha demethylase)
P154T (p.Pro154Thr) in CYP51A1 (Lanosterol 14-alpha demethylase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
P154T (p.Pro154Thr) variant details
- p.Pro154Thr
- gnomAD rs1320973894
- Missense
- Variant Prioritization Score for Impact Estimate 0.776
- REVEL 0.78
- MetaLR 0.75
- MetaSVM 0.67
- CADD 25.60
- PolyPhen-2 0.47
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available