A150G (p.Ala150Gly) variant of CYP51A1 (Lanosterol 14-alpha demethylase)
A150G (p.Ala150Gly) in CYP51A1 (Lanosterol 14-alpha demethylase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
A150G (p.Ala150Gly) variant details
- p.Ala150Gly
- TOPMed rs1819863457
- gnomAD rs1819863457
- Missense
- Variant Prioritization Score for Impact Estimate 0.577
- REVEL 0.56
- MetaLR 0.44
- MetaSVM -0.23
- CADD 26.80
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available