Y23C (p.Tyr23Cys) variant of CYP3A5 (Cytochrome P450 3A5)
Y23C (p.Tyr23Cys) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
Y23C (p.Tyr23Cys) variant details
- p.Tyr23Cys
- cosmic curated COSV56121
- TOPMed rs1812667577
- gnomAD rs1812667577
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.21
- CADD 26.00
- PolyPhen-2 0.89
- SIFT 0.01
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available