Y179F (p.Tyr179Phe) variant of CYP3A5 (Cytochrome P450 3A5)
Y179F (p.Tyr179Phe) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
Y179F (p.Tyr179Phe) variant details
- p.Tyr179Phe
- TOPMed rs1554420345
- Missense
- Variant Prioritization Score for Impact Estimate 0.457
- REVEL 0.34
- CADD 23.70
- PolyPhen-2 0.54
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available