W58S (p.Trp58Ser) variant of CYP3A5 (Cytochrome P450 3A5)
W58S (p.Trp58Ser) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
W58S (p.Trp58Ser) variant details
- p.Trp58Ser
- gnomAD rs1303343223
- Missense
- Variant Prioritization Score for Impact Estimate 0.205
- REVEL 0.15
- CADD 8.42
- PolyPhen-2 0.01
- SIFT 0.27
- Most common in the Non-Finnish European population (allele frequency 1.6e-05)
- Structural context available