W126R (p.Trp126Arg) variant of CYP3A5 (Cytochrome P450 3A5)
W126R (p.Trp126Arg) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
W126R (p.Trp126Arg) variant details
- p.Trp126Arg
- gnomAD rs1294331881
- Missense
- Variant Prioritization Score for Impact Estimate 0.742
- REVEL 0.81
- CADD 26.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the HGDP:MBUTI population (allele frequency 0.083)
- Structural context available