W12* (p.Trp12Ter) variant of CYP3A5 (Cytochrome P450 3A5)
W12* (p.Trp12Ter) in CYP3A5 (Cytochrome P450 3A5) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
W12* (p.Trp12Ter) variant details
- p.Trp12Ter
- TOPMed rs1288443539
- gnomAD rs1288443539
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.737
- CADD 34.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available