V89M (p.Val89Met) variant of CYP3A5 (Cytochrome P450 3A5)
V89M (p.Val89Met) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
V89M (p.Val89Met) variant details
- p.Val89Met
- cosmic curated COSV56118
- ExAC rs755699295
- TOPMed rs755699295
- gnomAD rs755699295
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.11
- CADD 12.90
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the 1KG:IBS population (allele frequency 0.017)
- Structural context available