T27N (p.Thr27Asn) variant of CYP3A5 (Cytochrome P450 3A5)
T27N (p.Thr27Asn) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
T27N (p.Thr27Asn) variant details
- p.Thr27Asn
- TOPMed rs1330633182
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.02
- CADD 10.90
- PolyPhen-2 0.04
- SIFT 0.07
- Most common in the Ashkenazi Jewish population (allele frequency 7.7e-05)
- Structural context available