T187I (p.Thr187Ile) variant of CYP3A5 (Cytochrome P450 3A5)
T187I (p.Thr187Ile) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
T187I (p.Thr187Ile) variant details
- p.Thr187Ile
- gnomAD rs1450180572
- Missense
- Variant Prioritization Score for Impact Estimate 0.516
- REVEL 0.40
- CADD 25.30
- PolyPhen-2 0.84
- SIFT 0.01
- Most common in the South Asian population (allele frequency 0.00044)
- Structural context available