T185I (p.Thr185Ile) variant of CYP3A5 (Cytochrome P450 3A5)
T185I (p.Thr185Ile) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
T185I (p.Thr185Ile) variant details
- p.Thr185Ile
- ExAC rs770303746
- gnomAD rs770303746
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.24
- CADD 23.60
- PolyPhen-2 0.90
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available