T136N (p.Thr136Asn) variant of CYP3A5 (Cytochrome P450 3A5)
T136N (p.Thr136Asn) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
T136N (p.Thr136Asn) variant details
- p.Thr136Asn
- 1000Genomes rs539204136
- ExAC rs539204136
- TOPMed rs539204136
- gnomAD rs539204136
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.23
- CADD 14.50
- PolyPhen-2 0.22
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available