T136A (p.Thr136Ala) variant of CYP3A5 (Cytochrome P450 3A5)
T136A (p.Thr136Ala) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
T136A (p.Thr136Ala) variant details
- p.Thr136Ala
- gnomAD rs1451231918
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- REVEL 0.13
- CADD 8.87
- PolyPhen-2 0.04
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 3.4e-06)
- Structural context available