T103K (p.Thr103Lys) variant of CYP3A5 (Cytochrome P450 3A5)
T103K (p.Thr103Lys) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
T103K (p.Thr103Lys) variant details
- p.Thr103Lys
- ExAC rs761882111
- TOPMed rs761882111
- gnomAD rs761882111
- Missense
- Variant Prioritization Score for Impact Estimate 0.668
- REVEL 0.61
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available