S188T (p.Ser188Thr) variant of CYP3A5 (Cytochrome P450 3A5)
S188T (p.Ser188Thr) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
S188T (p.Ser188Thr) variant details
- p.Ser188Thr
- ESP rs202148429
- ExAC rs202148429
- TOPMed rs202148429
- gnomAD rs202148429
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.17
- CADD 18.20
- PolyPhen-2 0.09
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available