S188* (p.Ser188Ter) variant of CYP3A5 (Cytochrome P450 3A5)
S188* (p.Ser188Ter) in CYP3A5 (Cytochrome P450 3A5) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
S188* (p.Ser188Ter) variant details
- p.Ser188Ter
- NCI-TCGA TCGA novel
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.738
- CADD 35.00
- UniProt: Variant assessed as somatic; high impact.
- Population evidence available
- Structural context available