S131* (p.Ser131Ter) variant of CYP3A5 (Cytochrome P450 3A5)
S131* (p.Ser131Ter) in CYP3A5 (Cytochrome P450 3A5) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
S131* (p.Ser131Ter) variant details
- p.Ser131Ter
- NCI-TCGA Cosmic COSV5612
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.606
- CADD 33.00
- UniProt: Variant assessed as somatic; high impact.
- Population evidence available
- Structural context available