S116T (p.Ser116Thr) variant of CYP3A5 (Cytochrome P450 3A5)
S116T (p.Ser116Thr) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
S116T (p.Ser116Thr) variant details
- p.Ser116Thr
- Ensembl rs200208768
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- REVEL 0.14
- CADD 2.07
- PolyPhen-2 0.02
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 1.6e-05)
- Structural context available