R91K (p.Arg91Lys) variant of CYP3A5 (Cytochrome P450 3A5)
R91K (p.Arg91Lys) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
R91K (p.Arg91Lys) variant details
- p.Arg91Lys
- ExAC rs767268743
- gnomAD rs767268743
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- REVEL 0.14
- CADD 10.20
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available