R158G (p.Arg158Gly) variant of CYP3A5 (Cytochrome P450 3A5)
R158G (p.Arg158Gly) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
R158G (p.Arg158Gly) variant details
- p.Arg158Gly
- Ensembl rs1811052127
- Missense
- Variant Prioritization Score for Impact Estimate 0.232
- REVEL 0.13
- CADD 23.00
- PolyPhen-2 0.14
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available