R105Q (p.Arg105Gln) variant of CYP3A5 (Cytochrome P450 3A5)
R105Q (p.Arg105Gln) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
R105Q (p.Arg105Gln) variant details
- p.Arg105Gln
- ExAC rs768977839
- TOPMed rs768977839
- gnomAD rs768977839
- Missense
- Variant Prioritization Score for Impact Estimate 0.558
- REVEL 0.43
- CADD 23.30
- PolyPhen-2 0.76
- SIFT 0.02
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available