R105G (p.Arg105Gly) variant of CYP3A5 (Cytochrome P450 3A5)
R105G (p.Arg105Gly) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
R105G (p.Arg105Gly) variant details
- p.Arg105Gly
- ExAC rs776567184
- gnomAD rs776567184
- Missense
- Variant Prioritization Score for Impact Estimate 0.45
- REVEL 0.44
- CADD 23.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.6e-05)
- Structural context available