P80R (p.Pro80Arg) variant of CYP3A5 (Cytochrome P450 3A5)
P80R (p.Pro80Arg) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
P80R (p.Pro80Arg) variant details
- p.Pro80Arg
- TOPMed rs1263327720
- gnomAD rs1263327720
- Missense
- Variant Prioritization Score for Impact Estimate 0.647
- REVEL 0.59
- CADD 22.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available