M145T (p.Met145Thr) variant of CYP3A5 (Cytochrome P450 3A5)
M145T (p.Met145Thr) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
M145T (p.Met145Thr) variant details
- p.Met145Thr
- ExAC rs764576184
- TOPMed rs764576184
- gnomAD rs764576184
- Missense
- Variant Prioritization Score for Impact Estimate 0.552
- REVEL 0.57
- CADD 24.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available