M114V (p.Met114Val) variant of CYP3A5 (Cytochrome P450 3A5)
M114V (p.Met114Val) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
M114V (p.Met114Val) variant details
- p.Met114Val
- TOPMed rs1488049313
- gnomAD rs1488049313
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.11
- CADD 16.40
- PolyPhen-2 0.35
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available