L82V (p.Leu82Val) variant of CYP3A5 (Cytochrome P450 3A5)
L82V (p.Leu82Val) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
L82V (p.Leu82Val) variant details
- p.Leu82Val
- ExAC rs745739575
- TOPMed rs745739575
- gnomAD rs745739575
- Missense
- Variant Prioritization Score for Impact Estimate 0.148
- REVEL 0.17
- CADD 6.93
- PolyPhen-2 0.52
- SIFT 0.03
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available