L82R (p.Leu82Arg) variant of CYP3A5 (Cytochrome P450 3A5)
L82R (p.Leu82Arg) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
L82R (p.Leu82Arg) variant details
- p.Leu82Arg
- ESP rs56244447
- ExAC rs56244447
- TOPMed rs56244447
- gnomAD rs56244447
- Missense
- Variant Prioritization Score for Impact Estimate 0.575
- REVEL 0.56
- CADD 23.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available