L51F (p.Leu51Phe) variant of CYP3A5 (Cytochrome P450 3A5)
L51F (p.Leu51Phe) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
L51F (p.Leu51Phe) variant details
- p.Leu51Phe
- gnomAD rs1377271967
- Missense
- Variant Prioritization Score for Impact Estimate 0.28
- REVEL 0.09
- CADD 9.90
- PolyPhen-2 0.18
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available