L36R (p.Leu36Arg) variant of CYP3A5 (Cytochrome P450 3A5)
L36R (p.Leu36Arg) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
L36R (p.Leu36Arg) variant details
- p.Leu36Arg
- ExAC rs776441407
- gnomAD rs776441407
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.21
- CADD 13.50
- PolyPhen-2 0.03
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available