L160W (p.Leu160Trp) variant of CYP3A5 (Cytochrome P450 3A5)
L160W (p.Leu160Trp) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
L160W (p.Leu160Trp) variant details
- p.Leu160Trp
- TOPMed rs1027101735
- Missense
- Variant Prioritization Score for Impact Estimate 0.545
- REVEL 0.55
- CADD 26.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 7.7e-05)
- Structural context available